Administered by:
University of Cambridge
Walton Street
The street runs north from the western end of Beaumont Street and the northern end of Worcester Street by the main entrance of Worcester College. The Clarendon Institute building, which houses the Oxford Centre for Hebrew and Jewish Studies, is on the east side of the street. Somerville College, one of the former women-only colleges, also backs onto the street. The Oxford University Press (just south of the junction with Great Clarendon Street) and the original location of Ruskin College are on the west side of the street, the former Church of England parish church of Saint Paul on the east side is almost opposite the OUP and St Sepulchre's Cemetery is off the street to the west.

The Jericho Tavern is a public house and music venue at 56 Walton Street. In the late 1980s and early 1990s it was an important part of the music scene in Oxford, spawning the groups Ride, Radiohead and Supergrass.

In 2015, a new controversial building for the Blavatnik School of Government of Oxford University on the Radcliffe Observatory Quarter site, designed by Herzog & de Meuron, was opened immediately opposite the Oxford University Press building, dominating the location with its height (taller than Carfax Tower), and resulting in further removal of the high stone wall behind the old Infirmary site. Exeter College is developing the Ruskin site opposite to the south for college accommodation.

Little Clarendon Street, a shopping street, links Walton Street with Saint Giles. There are numerous restaurants on Walton Street, often used by Oxford University students because of its central position, such as Branca, Loch Fyne, The Jericho Cafe, Arzoo, Posh Fish, Brasserie Blanc (associated with the chef Raymond Blanc) and The Standard Tandoori. Oxford's main independent art house cinema, the Phoenix Picturehouse, is on the west side of the street. A number of cocktail bars and pubs can be found on Walton Street.

Other shops include the speciality florist Daisies and Branca Delicatessen.

Northwards the street continues as Kingston Road through Walton Manor, at a junction with Walton Well Road to the northwest towards Port Meadow and St Bernard's Road to the east, linking with Woodstock Road. Near the northern end of Walton Street, Observatory Street also links Woodstock Road to the east.